Literature summary for 7.1.1.9 extracted from

Ammari, M.; Lecomte, A.; Sakly, M.; Abdelmelek, H.; de-Seze, R.
Exposure to GSM 900 MHz electromagnetic fields affects cerebral cytochrome c oxidase activity (2008), Toxicology, 250, 70-74.

Search for more literature for 7.1.1.9

Application

Application	Comment	Organism
medicine	6W/Kg GSM 900MHz microwaves may affect brain metabolism and neuronal activity (cytochrome c oxidase activity) in rats	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	rats exposed to a GSM signal at 6W/Kg show decreased CO activity in some areas of the prefrontal and frontal cortex (infralimbic cortex, prelimbic cortex, primary motor cortex, secondary motor cortex, anterior cingulate cortex areas 1 and 2), the septum (dorsal and ventral parts of the lateral septal nucleus), the hippocampus (dorsal field CA1, CA2 and CA3 of the hippocampus and dental gyrus) and the posterior cortex (retrosplenial agranular cortex, primary and secondary visual cortex, perirhinal cortex and lateral entorhinal cortex). Exposure to GSM at 1.5W/Kg does not affect brain activity	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Rattus norvegicus	5739	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	male sprague-dawley rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-
cerebral cortex	frontal cortex and posterior cortex	Rattus norvegicus	-
hippocampus	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
reduced horse heart cytochrome c + O2 + H+	-	Rattus norvegicus	oxidized horse heart cytochrome c + H2O	-	?

Synonyms

Synonyms	Comment	Organism
cytochrome c oxidase	-	Rattus norvegicus

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Release 2023.1 (January 2023)