Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | synthetic models of the active site of cytochrome c oxidase [(LN4-OH)CuI-FeII(TMP)]+ and [(LN3-OH)CuI-FeII(TMP)]+ | synthetic construct |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu | reduction of dioxygen to water takes place at the heme a3-CuB binuclear center | synthetic construct | |
Fe2+ | - |
synthetic construct |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
synthetic construct | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | oxygenation of the tetradentate model both in MeCN and in other solvents produces a low-temperature-stable dioxygen-bridged peroxide with an O-O stretching vibration at 799 cm-1. Oxygenation of the tridentate model in EtCN solution generates a heme superoxide species with the copper moiety oxidized to copper(II). Coexistence of a heme superoxide and a bridged peroxide species in equivalent amounts when the oxygenation reaction is carried out in CH2Cl2/7% EtCN | synthetic construct | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CCO | - |
synthetic construct |
cytochrome c oxidase | - |
synthetic construct |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | reduction of dioxygen to water takes place at the heme a3-CuB binuclear center | synthetic construct |