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Literature summary for 7.1.1.9 extracted from

  • Chapman, E.G.; Piontkivska, H.; Walker, J.M.; Stewart, D.T.; Curole, J.P.; Hoeh, W.R.
    Extreme primary and secondary protein structure variability in the chimeric male-transmitted cytochrome c oxidase subunit II protein in freshwater mussels: evidence for an elevated amino acid substitution rate in the face of domain-specific purifying sele (2008), BMC Evol. Biol., 8, 165.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Hamiota subangulata
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Pronodularia japanensis
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Lampsilis hydiana
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Lampsilis ovata
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Lampsilis straminea
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Lemiox rimosus
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Obliquaria reflexa
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Obovaria olivaria
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Plectomerus dombeyanus
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Pleurobema sintoxia
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Popenaias popeii
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Ptychobranchus fasciolaris
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Quadrula quadrula
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Cyclonaias pustulosa
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Toxolasma glans
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Venustaconcha ellipsiformis
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Ortmanniana ligamentina
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Amblema plicata
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Cyrtonaias tampicoensis
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Fusconaia flava
additional information the MCOX2e region is unique to unionoidean bivalve male genomes. MCOX2e is functional and is likely the result of a single insertion event that took place over 65 MYA, the predicted transmembrane helices/interhelical loops number, length and position variability likely stems from substitution-based processes rather than the typically implicated insertion/deletion events. MCOX2e has relatively high rates of evolution in its primary and secondary structures. MCOX2e displays evidence suggestive of site-specific positive selection. MCOX2e has an overall pattern of purifying selection that leads to the preservation of the transmembrane helices/interhelical loops and hydrophilic C-terminus tail sub-regions, and the more conserved C-terminus tail (relative to the transmembrane helices/interhelical loops sub-region of MCOX2e) is likely biologically active because it contains functional motifs. MCOX2e may have a novel reproductive function within unionoidean bivalves Glebula rotundata

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Lampsilis straminea 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Lemiox rimosus 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Obliquaria reflexa 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Obovaria olivaria 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Plectomerus dombeyanus 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Pleurobema sintoxia 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Popenaias popeii 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Ptychobranchus fasciolaris 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Quadrula quadrula 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Cyclonaias pustulosa 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Toxolasma glans 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Venustaconcha ellipsiformis 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Ortmanniana ligamentina 16020
-
membrane the near N-terminus ca. 2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Amblema plicata 16020
-
membrane the near N-terminus ca.2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Hamiota subangulata 16020
-
membrane the near N-terminus ca.2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Pronodularia japanensis 16020
-
membrane the near N-terminus ca.2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Lampsilis hydiana 16020
-
membrane the near N-terminus ca.2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Lampsilis ovata 16020
-
membrane the near N-terminus ca.2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Cyrtonaias tampicoensis 16020
-
membrane the near N-terminus ca.2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Fusconaia flava 16020
-
membrane the near N-terminus ca.2/3 of the MCOX2e region contains an interspecifically variable number of predicted transmembrane helices Glebula rotundata 16020
-

Organism

Organism UniProt Comment Textmining
Amblema plicata B3SGB2
-
-
Cyclonaias pustulosa Q8LWE9
-
-
Cyrtonaias tampicoensis B3SGB6
-
-
Fusconaia flava B3SGC4
-
-
Glebula rotundata B3SGC1
-
-
Hamiota subangulata B3SGC2
-
-
Lampsilis hydiana B3SGB5
-
-
Lampsilis ovata B3SGC0
-
-
Lampsilis straminea B3SGB4
-
-
Lemiox rimosus B3SGB9
-
-
Obliquaria reflexa B3SGA9
-
-
Obovaria olivaria B3SGC3
-
-
Ortmanniana ligamentina B3SGB7
-
-
Plectomerus dombeyanus B3SGA7
-
-
Pleurobema sintoxia B3SGA8
-
-
Popenaias popeii B3SGB1
-
-
Pronodularia japanensis Q94QP4
-
-
Ptychobranchus fasciolaris B3SGB8
-
-
Quadrula quadrula B3SGC5
-
-
Toxolasma glans B3SGB0
-
-
Venustaconcha ellipsiformis A0ASV2
-
-

Synonyms

Synonyms Comment Organism
cytochrome oxidase subunit II
-
Hamiota subangulata
cytochrome oxidase subunit II
-
Pronodularia japanensis
cytochrome oxidase subunit II
-
Lampsilis hydiana
cytochrome oxidase subunit II
-
Lampsilis ovata
cytochrome oxidase subunit II
-
Lampsilis straminea
cytochrome oxidase subunit II
-
Lemiox rimosus
cytochrome oxidase subunit II
-
Obliquaria reflexa
cytochrome oxidase subunit II
-
Obovaria olivaria
cytochrome oxidase subunit II
-
Plectomerus dombeyanus
cytochrome oxidase subunit II
-
Pleurobema sintoxia
cytochrome oxidase subunit II
-
Popenaias popeii
cytochrome oxidase subunit II
-
Ptychobranchus fasciolaris
cytochrome oxidase subunit II
-
Quadrula quadrula
cytochrome oxidase subunit II
-
Cyclonaias pustulosa
cytochrome oxidase subunit II
-
Toxolasma glans
cytochrome oxidase subunit II
-
Venustaconcha ellipsiformis
cytochrome oxidase subunit II
-
Ortmanniana ligamentina
cytochrome oxidase subunit II
-
Amblema plicata
cytochrome oxidase subunit II
-
Cyrtonaias tampicoensis
cytochrome oxidase subunit II
-
Fusconaia flava
cytochrome oxidase subunit II
-
Glebula rotundata
MCOX2
-
Hamiota subangulata
MCOX2
-
Pronodularia japanensis
MCOX2
-
Lampsilis hydiana
MCOX2
-
Lampsilis ovata
MCOX2
-
Lampsilis straminea
MCOX2
-
Lemiox rimosus
MCOX2
-
Obliquaria reflexa
MCOX2
-
Obovaria olivaria
MCOX2
-
Plectomerus dombeyanus
MCOX2
-
Pleurobema sintoxia
MCOX2
-
Popenaias popeii
MCOX2
-
Ptychobranchus fasciolaris
MCOX2
-
Quadrula quadrula
MCOX2
-
Cyclonaias pustulosa
MCOX2
-
Toxolasma glans
MCOX2
-
Venustaconcha ellipsiformis
MCOX2
-
Ortmanniana ligamentina
MCOX2
-
Amblema plicata
MCOX2
-
Cyrtonaias tampicoensis
MCOX2
-
Fusconaia flava
MCOX2
-
Glebula rotundata