Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | segments of human skeletal muscle fibers harboring two pathogenic mitochondrial DNA mutations retain normal COX activity by maintaining a minimum amount of wild-type mitochondrial DNA | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | high percentage levels of mutated mitochondrial DNA are associated with a dramatic reduction in wild-type levels and COX deficiency. For the m.3243ArG mutation, a superabundance of wild-type mitochondrial DNA is found in many muscle-fiber sections with negligible COX activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle fiber | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
COX | - |
Homo sapiens |
cytochrome c oxidase | - |
Homo sapiens |