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Literature summary for 7.1.1.9 extracted from

  • Victor, E.G.; Zanette, F.; Aguiar, M.R.; Aguiar, C.S.; Cardoso, D.C.; Cristiano, M.P.; Streck, E.L.; Paula, M.M.
    Effect of ruthenium complexes on the activities of succinate dehydrogenase and cytochrome oxidase (2007), Chem. Biol. Interact., 170, 59-66.
    View publication on PubMed
Search for more literature for 7.1.1.9

Activating Compound

Activating Compound Comment Organism Structure
trans-[RuCl2(3,4-pyridinedicarboxylic acid)4]Cl increases COX activity in hippocampus, striatum and cerebral cortex Rattus norvegicus
trans-[RuCl2(3,5-pyridinedicarboxylic acid)4] increases COX activity in hippocampus, striatum, cerebral cortex and kidney Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
trans-[RuCl2(3,4-pyridinedicarboxylic acid)4]Cl inhibits COX activity in kidney Rattus norvegicus
trans-[RuCl2(3-pyridinecarboxylic acid)4] inhibits COX activity in heart and kidney Rattus norvegicus
trans-[RuCl2(4-pyridinecarboxylic acid)4] inhibits COX activity in hippocampus, heart, liver and kidney Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 adult male Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
cerebral cortex
-
 Rattus norvegicus
-
heart
-
 Rattus norvegicus
-
hippocampus
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
additional information striatum Rattus norvegicus
-
skeletal muscle
-
 Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
COX
-
 Rattus norvegicus
cytochrome oxidase
-
 Rattus norvegicus