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Literature summary for 7.1.1.9 extracted from

  • Yamazaki, T.; Fukumori, Y.; Yamanaka, T.
    Catalytic properties of cytochrome c oxidase purified from Nitrosomonas europaea (1988), J. Biochem., 103, 499-503.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
cardiolipin
-
Nitrobacter winogradskyi
cardiolipin activation if horse heart or Candida krusei cytchrome c are used as electron donors Nitrosomonas europaea
additional information no activation with Tween 20, Triton X-100 or phosphatidylcholin Nitrosomonas europaea
phosphatidylcholine 2.7fold activation of horse heart cytochrome c mediated reaction, 3fold activation of Candida krusei cytchrome c mediated reaction Nitrosomonas europaea
phosphatidylinositol 2.1fold activation of horse heart cytochrome c mediated reaction, 2.4fold activation of Candida krusei cytchrome c mediated reaction Nitrosomonas europaea
phosphatidylserine 7.2fold activation of horse heart cytochrome c mediated reaction, 4.7fold activation of Candida krusei cytchrome c mediated reaction Nitrosomonas europaea
poly-L-lysine strong activation of Nitrosomonas europaea cytochrome c oxidation Nitrosomonas europaea
sodium cholate 0.5%, activation if horse heart or Candida krusei cytchrome c are used as electron donors Nitrosomonas europaea
sodiumdodecylsulfate 0.01%, strong activation if horse heart or Candida krusei cytchrome c are used as electron donors Nitrosomonas europaea

Inhibitors

Inhibitors Comment Organism Structure
nonionic detergents
-
Nitrosomonas europaea
poly-L-lysine complete inhibition of horse and Candida krusei cytochrome c oxidation with 0.0001 mM and 0.002 mM poly-L-lysine, respectively Nitrosomonas europaea

Organism

Organism UniProt Comment Textmining
Nitrobacter winogradskyi
-
-
-
Nitrosomonas europaea
-
-
-

Storage Stability

Storage Stability Organism
liquid N2, 10 mM Tris-HCl buffer, pH 8.0, 0.5% Tween 20 Nitrosomonas europaea
liquid N2, 10 mM Tris-HCl buffer, pH 8.0, 0.5% Tween 20 Nitrobacter winogradskyi

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ferrocytochrome c + O2 horse ferrocytochrome c Nitrosomonas europaea ferricytochrome c + H2O
-
?
ferrocytochrome c + O2 horse ferrocytochrome c Nitrobacter winogradskyi ferricytochrome c + H2O
-
?
ferrocytochrome c + O2 Candida krusei ferrocytochrome c Nitrosomonas europaea ferricytochrome c + H2O
-
?
ferrocytochrome c + O2 Candida krusei ferrocytochrome c Nitrobacter winogradskyi ferricytochrome c + H2O
-
?
ferrocytochrome c + O2 Nitrosomonas europaea cytochrome c Nitrosomonas europaea ferricytochrome c + H2O
-
?
ferrocytochrome c + O2 Nitrosomonas europaea cytochrome c Nitrobacter winogradskyi ferricytochrome c + H2O
-
?