Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(n-heptyl)-4-hydroxyquinoline-N-oxide | - |
Bacillus subtilis | |
antimycin A | more than 10fold less effective than 2-(n-heptyl)-4-hydroxyquinoline-N-oxide, 39% residual activity at 0.01 mM | Bacillus subtilis | |
cyanide | 47% residual activity at 0.5 mM | Bacillus subtilis | |
Myxothiazol | more than 10fold less effective than 2-(n-heptyl)-4-hydroxyquinoline-N-oxide, 45% residual activity at 0.01 mM | Bacillus subtilis | |
Stigmatellin | more than 10fold less effective than 2-(n-heptyl)-4-hydroxyquinoline-N-oxide, 39% residual activity at 0.01 mM | Bacillus subtilis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Bacillus subtilis | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
13686 | - |
1 * 33640 + 1 * 73834 + 1 * 22670 + 1 * 13686, subunits QoxA, QoxB, QoxC and QoxD, calculated from sequence of cDNA | Bacillus subtilis |
15000 | - |
1 * 36000 + 1 * 54000 + 1 * 20000 + 1 * 15000, subunits QoxA, QoxB, QoxC and QoxD, SDS-PAGE | Bacillus subtilis |
20000 | - |
1 * 36000 + 1 * 54000 + 1 * 20000 + 1 * 15000, subunits QoxA, QoxB, QoxC and QoxD, SDS-PAGE | Bacillus subtilis |
22670 | - |
1 * 33640 + 1 * 73834 + 1 * 22670 + 1 * 13686, subunits QoxA, QoxB, QoxC and QoxD, calculated from sequence of cDNA | Bacillus subtilis |
33640 | - |
1 * 33640 + 1 * 73834 + 1 * 22670 + 1 * 13686, subunits QoxA, QoxB, QoxC and QoxD, calculated from sequence of cDNA | Bacillus subtilis |
36000 | - |
1 * 36000 + 1 * 54000 + 1 * 20000 + 1 * 15000, subunits QoxA, QoxB, QoxC and QoxD, SDS-PAGE | Bacillus subtilis |
54000 | - |
1 * 36000 + 1 * 54000 + 1 * 20000 + 1 * 15000, subunits QoxA, QoxB, QoxC and QoxD, SDS-PAGE | Bacillus subtilis |
73834 | - |
1 * 33640 + 1 * 73834 + 1 * 22670 + 1 * 13686, subunits QoxA, QoxB, QoxC and QoxD, calculated from sequence of cDNA | Bacillus subtilis |
144000 | - |
calculated from sequence of cDNA | Bacillus subtilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
menaquinol + O2 | Bacillus subtilis | - |
menaquinone + H2O | - |
? | |
menaquinol + O2 | Bacillus subtilis W23 | - |
menaquinone + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Bacillus subtilis W23 | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
culture condition:glucose-grown cell | - |
Bacillus subtilis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 2,3-dimethyl-1,4-naphthoquinol + O2 + n H+[side 1] | best substrate | Bacillus subtilis | 2 2,3-dimethyl-1,4-naphthoquinone + 2 H2O + n H+[side 2] | - |
? | |
2 2,3-dimethyl-1,4-naphthoquinol + O2 + n H+[side 1] | best substrate | Bacillus subtilis W23 | 2 2,3-dimethyl-1,4-naphthoquinone + 2 H2O + n H+[side 2] | - |
? | |
menadiol + O2 + n H+[side 1] | - |
Bacillus subtilis | menadione + H2O + n H+[side 2] | - |
? | |
menadiol + O2 + n H+[side 1] | - |
Bacillus subtilis W23 | menadione + H2O + n H+[side 2] | - |
? | |
menaquinol + O2 | - |
Bacillus subtilis | menaquinone + H2O | - |
? | |
menaquinol + O2 | - |
Bacillus subtilis W23 | menaquinone + H2O | - |
? | |
additional information | no activity with 1,4-naphthoquinol, N,N,N',N'-tetramethyl-1,4-phenylenediamine plus ascorbate or reduced cytochrome c | Bacillus subtilis | ? | - |
? | |
additional information | no activity with 1,4-naphthoquinol, N,N,N',N'-tetramethyl-1,4-phenylenediamine plus ascorbate or reduced cytochrome c | Bacillus subtilis W23 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterotetramer | 1 * 33640 + 1 * 73834 + 1 * 22670 + 1 * 13686, subunits QoxA, QoxB, QoxC and QoxD, calculated from sequence of cDNA | Bacillus subtilis |
heterotetramer | 1 * 36000 + 1 * 54000 + 1 * 20000 + 1 * 15000, subunits QoxA, QoxB, QoxC and QoxD, SDS-PAGE | Bacillus subtilis |
Synonyms | Comment | Organism |
---|---|---|
menaquinol oxidase (aa3-600) | - |
Bacillus subtilis |
Qox | - |
Bacillus subtilis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome | the enzyme contains 7 mol cytochrome aa 3 per g protein which corresponds to 2 mol heme A per mol enzyme | Bacillus subtilis |