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Literature summary for 7.1.1.3 extracted from

  • Forte, E.; Borisov, V.B.; Falabella, M.; Colaco, H.G.; Tinajero-Trejo, M.; Poole, R.K.; Vicente, J.B.; Sarti, P.; Giuffre, A.
    The terminal oxidase cytochrome bd promotes sulfide-resistant bacterial respiration and growth (2016), Sci. Rep., 6, 23788 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.1.1.3

Inhibitors

Inhibitors Comment Organism Structure
additional information enzyme is insensitive to sulfide up to 0.058 mM Escherichia coli
Sulfide
-
 Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0ABJ1 and P0ABI8 and P0ABJ3 and P0ABJ6 P0ABJ1 i.e. subunit cyoA, P0ABI8 i.e. subunit cyoB, P0ABJ3 i.e. subunit cyoC, P0ABJ6 i.e. subunit cyoD
-
Escherichia coli P26459 and P26458 P26459 i.e. subunit appC, P26458 i.e. subunit appB
-

Synonyms

Synonyms Comment Organism
appB
-
 Escherichia coli
appC
-
 Escherichia coli
cyoA
-
 Escherichia coli
cyoB
-
 Escherichia coli
cyoC
-
 Escherichia coli
cyoD
-
 Escherichia coli
cytochrome bd-II ubiquinol oxidase
-
 Escherichia coli
cytochromes bo3 oxidase
-
 Escherichia coli

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0011
-
 pH 7.4, 25°C Escherichia coli Sulfide

General Information

General Information Comment Organism
physiological function in respiratory mutants, both O2-consumption and aerobic growth are severely impaired by sulfide when respiration is sustained by the bo3 oxidase alone Escherichia coli
physiological function in respiratory mutants, both O2-consumption and aerobic growth are unaffected by up to 200 microM sulfide when cytochrome bd-I or bd-II enzyme actes as the only terminal oxidase. Wild-type Escherichia coli shows sulfide-insensitive respiration and growth under conditions favouring the expression of bd oxidases Escherichia coli