Literature summary for 7.1.1.2 extracted from

Yang, X.Y.; He, K.; Pan, C.S.; Li, Q.; Liu, Y.Y.; Yan, L.; Wei, X.H.; Hu, B.H.; Chang, X.; Mao, X.W.; Huang, D.D.; Wang, L.J.; Hu, S.W.; Jiang, Y.; Wang, G.C.; Fan, J.Y.; Fan, T.P.; Han, J.Y.
3, 4-dihydroxyl-phenyl lactic acid restores NADH dehydrogenase 1 alpha subunit 10 to ameliorate cardiac reperfusion injury (2015), Sci. Rep., 5, 10739 .

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Application

Application	Comment	Organism
medicine	in rats subjected to left descending artery occlusion followed by reperfusion, treatment with 3,4-dihydroxyl-phenyl lactic acid ameliorates myocardial structure and function disorder, blunts the impairment of Complex I activity and mitochondrial function after ischemia/reperfusion. 3,4-Dihydroxyl-phenyl lactic acid DLA is able to prevent ischemia/reperfusion-induced decrease in NDUFA10 expression, improve complex I activity and mitochondrial function, eventually attenuate cardiac structure and function injury after ischemia/reperfusion	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	Q561S0	-	-

Synonyms

Synonyms	Comment	Organism
NADH dehydrogenase [ubiquinone] 1	alpha subcomplex subunit 10	Rattus norvegicus
Ndufa10	-	Rattus norvegicus

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Release 2023.1 (January 2023)