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Literature summary for 7.1.1.1 extracted from

  • Sundaresan, V.; Chartron, J.; Yamaguchi, M.; Stout, C.D.
    Conformational diversity in NAD(H) and interacting transhydrogenase nicotinamide nucleotide binding domains (2005), J. Mol. Biol., 346, 617-629.
    View publication on PubMed
Search for more literature for 7.1.1.1

Cloned(Commentary)

Cloned (Comment) Organism
domain dI and His-tag fusion protein of dIII separately expressed in Escherichia coli Rhodospirillum rubrum

Crystallization (Commentary)

Crystallization (Comment) Organism
domain dIII, domain dI dimer and dI2dIII complex in the presence of limiting NADH using the vapor diffusion method Rhodospirillum rubrum

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rhodospirillum rubrum 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADH + NADP+ Rhodospirillum rubrum links hydride transfer between NAD(H) and NADP(H) to the outside in translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione, reaction is stereospecific between th 4A position of NAD(H) to the 4B position of NADP(H) NAD+ + NADPH
-
 r

Organism

Organism UniProt Comment Textmining
Rhodospirillum rubrum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + NADP+
-
 Rhodospirillum rubrum NAD+ + NADPH
-
 r
NADH + NADP+ links hydride transfer between NAD(H) and NADP(H) to the outside in translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione, reaction is stereospecific between th 4A position of NAD(H) to the 4B position of NADP(H) Rhodospirillum rubrum NAD+ + NADPH
-
 r

Subunits

Subunits Comment Organism
dimer isolated dI domains Rhodospirillum rubrum
trimer dI2dIII trimers formed in mixtures of recombinant dI and dIII domains Rhodospirillum rubrum

Cofactor

Cofactor Comment Organism Structure
NAD(P)+
-
 Rhodospirillum rubrum
NAD(P)H
-
 Rhodospirillum rubrum