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Literature summary for 6.5.1.8 extracted from
- RTCB-1 mediates neuroprotection via XBP-1 mRNA splicing in the unfolded protein response pathway (2014), J. Neurosci., 34, 16076-16085 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Rtcb-1 | - |
Caenorhabditis elegans |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | RNAi knockdown of rtcb-1 lowers endoplasmic reticulum stress response in vivo | Caenorhabditis elegans |
| metabolism | the enzyme is necessary for xbp-1 mRNA splicing | Caenorhabditis elegans |
| physiological function | the enzyme protects Caenorhabditis elegans dopamine neurons from age-dependent degeneration induced by human alpha-synuclein or 6-hyroxydopamine | Caenorhabditis elegans |
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Release 2023.1 (January 2023)
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