Application | Comment | Organism |
---|---|---|
medicine | regulated repression of the enzyme blocks editing, this repression is lethal in bloodforms of the parasite, indicating that editing is essential in the mammalian stage of the life cycle, the editing complex, which is present in all kinetoplastid parasites, may thus be a chemotherapeutic target | Trypanosoma brucei |
Cloned (Comment) | Organism |
---|---|
- |
Trypanosoma brucei |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Trypanosoma brucei | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (ribonucleotide)n + (ribonucleotide)m | Trypanosoma brucei | RNA editing, essential for proliferation of Trypanosoma brucei | AMP + diphosphate + (ribonucleotide)n+m | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
- |
- |
Purification (Comment) | Organism |
---|---|
editing complex | Trypanosoma brucei |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (ribonucleotide)n + (ribonucleotide)m | - |
Trypanosoma brucei | AMP + diphosphate + (ribonucleotide)n+m | - |
? | |
ATP + (ribonucleotide)n + (ribonucleotide)m | RNA editing, essential for proliferation of Trypanosoma brucei | Trypanosoma brucei | AMP + diphosphate + (ribonucleotide)n+m | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TbMP52 | macromolecular complex with RNA ligase activity | Trypanosoma brucei |