Any feedback?
Literature summary for 6.5.1.2 extracted from
- NAD homeostasis in the bacterial response to DNA/RNA damage (2014), DNA Repair, 23, 17-26 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Gluconobacter oxydans | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? |  |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Desulfovibrio vulgaris | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Thermotoga maritima | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Syntrophotalea carbinolica | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Oleidesulfovibrio alaskensis | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Synechococcus elongatus | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | Lawsonia intracellularis | - |
(deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Desulfovibrio vulgaris | - |
- |
- |
| Gluconobacter oxydans | - |
- |
- |
| Lawsonia intracellularis | - |
- |
- |
| Oleidesulfovibrio alaskensis | - |
- |
- |
| Synechococcus elongatus | - |
- |
- |
| Syntrophotalea carbinolica | - |
- |
- |
| Thermotoga maritima | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Gluconobacter oxydans | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Desulfovibrio vulgaris | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Thermotoga maritima | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Syntrophotalea carbinolica | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Oleidesulfovibrio alaskensis | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Synechococcus elongatus | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
| NAD+ + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m | - |
Lawsonia intracellularis | (deoxyribonucleotide)n+m + AMP + beta-nicotinamide D-nucleotide | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LigA | - |
Gluconobacter oxydans |
| LigA | - |
Desulfovibrio vulgaris |
| LigA | - |
Thermotoga maritima |
| LigA | - |
Syntrophotalea carbinolica |
| LigA | - |
Oleidesulfovibrio alaskensis |
| LigA | - |
Synechococcus elongatus |
| LigA | - |
Lawsonia intracellularis |
| NAD-dependent DNA ligase | - |
Gluconobacter oxydans |
| NAD-dependent DNA ligase | - |
Desulfovibrio vulgaris |
| NAD-dependent DNA ligase | - |
Thermotoga maritima |
| NAD-dependent DNA ligase | - |
Syntrophotalea carbinolica |
| NAD-dependent DNA ligase | - |
Oleidesulfovibrio alaskensis |
| NAD-dependent DNA ligase | - |
Synechococcus elongatus |
| NAD-dependent DNA ligase | - |
Lawsonia intracellularis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Gluconobacter oxydans | |
| NAD+ | - |
Desulfovibrio vulgaris | |
| NAD+ | - |
Thermotoga maritima | |
| NAD+ | - |
Syntrophotalea carbinolica | |
| NAD+ | - |
Oleidesulfovibrio alaskensis | |
| NAD+ | - |
Synechococcus elongatus | |
| NAD+ | - |
Lawsonia intracellularis | |
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