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Literature summary for 6.4.1.2 extracted from

  • Li, X.; Ilarslan, H.; Brachova, L.; Qian, H.R.; Li, L.; Che, P.; Wurtele, E.S.; Nikolau, B.J.
    Reverse-genetic analysis of the two biotin-containing subunit genes of the heteromeric acetyl-coenzyme A carboxylase in Arabidopsis indicates a unidirectional functional redundancy (2011), Plant Physiol., 155, 293-314.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.4.1.2

Localization

Localization Comment Organism GeneOntology No. Textmining
plastid
-
 Arabidopsis thaliana 9536
-

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Arabidopsis thaliana
-
endosperm
-
 Arabidopsis thaliana
-
flower
-
 Arabidopsis thaliana
-
seed
-
 Arabidopsis thaliana
-
seedling
-
 Arabidopsis thaliana
-
silique
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + acetyl-CoA + HCO3-
-
 Arabidopsis thaliana ADP + malonyl-CoA + phosphate
-
 ?

Subunits

Subunits Comment Organism
heteromer the enzyme is composed of four subunits: biotin carboxyl carrier protein, biotin carboxylase, alpha-carboxyltransferase, and beta-carboxyltransferase Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
ACCase
-
 Arabidopsis thaliana
BCCP1 subunit Arabidopsis thaliana
BCCP2 subunit Arabidopsis thaliana
CAC1A gene name for subunit BCCP1 Arabidopsis thaliana
CAC1B gene name for subunit BCCP2 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Arabidopsis thaliana
biotin
-
 Arabidopsis thaliana

Expression

Organism Comment Expression
Arabidopsis thaliana accumulation of BCCP1 is 5ffold higher than that of BCCP2 in developing siliques up

General Information

General Information Comment Organism
malfunction transfer DNA insertional alleles that completely eliminate the accumulation of subunit BCCP2 have no perceptible effect on plant growth, development, and fatty acid accumulation. In contrast, transfer DNA insertional null allele of the CAC1A gene for subunit BCCP1 is embryo lethal and deleteriously affects pollen development and germination. Reducing BCCP1 accumulation to 35% of wild type levels, decreases fatty acid accumulation and severely affects normal vegetative plant growth Arabidopsis thaliana
metabolism ACCase is a key enzyme for de novo fatty acid biosynthesis Arabidopsis thaliana
physiological function ACCase is essential for plant seed development Arabidopsis thaliana