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Literature summary for 6.4.1.2 extracted from

  • Oh, W.; Abu-Elheiga, L.; Kordari, P.; Gu, Z.; Shaikenov, T.; Chirala, S.S.; Wakil, S.J.
    Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice (2005), Proc. Natl. Acad. Sci. USA, 102, 1384-1389.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.4.1.2

Cloned(Commentary)

Cloned (Comment) Organism
expression analysis of genes involved in energy metabolism, including gene Acc2, in wild-type and Acc2-knockout mutant mice Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information ACC2 knockout mutant mice are protected against diet-induced obesity and diabetes and show a 80% increased palmitate oxidation level in adipocytes which remains increased in presence of insulin, also the glucose oxidation is 2fold increased in mutant mice compared to wild-type mice Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus isozymes ACC1 and ACC2 play roles in lipid metabolism in adipose tissue, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 male mice
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Source Tissue

Source Tissue Comment Organism Textmining
adipocyte
-
 Mus musculus
-
adipose tissue
-
 Mus musculus
-
epididymis fat pads Mus musculus
-
fat pad epididymis Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information isozymes ACC1 and ACC2 play roles in lipid metabolism in adipose tissue, overview Mus musculus ?
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 ?

Synonyms

Synonyms Comment Organism
ACC2
-
 Mus musculus
acetyl-CoA carboxylase 2
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus