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Literature summary for 6.4.1.2 extracted from

  • Herbert, D.; Alban, C.; Cole, D.J.; Pallett, K.E.; Harwood, J.L.
    Characteristics of two forms of acetyl-CoA carboxylase from maize leaves (1994), Biochem. Soc. Trans., 22, 261S.
    View publication on PubMed
Search for more literature for 6.4.1.2

Inhibitors

Inhibitors Comment Organism Structure
Quizalofop mesophyll chloroplast isoform reveals 1000fold greater sensitivity than non-mesophyll chloroplast isoform Zea mays

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.04
-
 ATP non-mesophyll chloroplast isoform Zea mays
0.05
-
 acetyl-CoA mesophyll chloroplast isoform Zea mays
0.09
-
 acetyl-CoA non-mesophyll chloroplast isoform Zea mays
0.095
-
 acetyl-CoA mesophyll chloroplast isoform Zea mays
0.6
-
 HCO3- non-mesophyll chloroplast isoform Zea mays
1.2
-
 acetyl-CoA mesophyll chloroplast isoform Zea mays

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast 2 isoforms: non-mesophyll chloroplast form and mesophyll chloroplast form Zea mays 9507
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
220000
-
 2 * 220000, non-mesophyll chloroplast isoform, SDS-PAGE Zea mays
230000
-
 2 * 230000, mesophyll chloroplast isoform, SDS-PAGE Zea mays

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + acetyl-CoA + HCO3- Zea mays key role in lipid metabolism ?
-
 ?

Organism

Organism UniProt Comment Textmining
Zea mays
-
 2 isoforms: non-mesophyll chloroplast form and mesophyll chloroplast form
-

Purification (Commentary)

Purification (Comment) Organism
2 isoforms: non-mesophyll chloroplast form and mesophyll chloroplast form Zea mays

Reaction

Reaction Comment Organism Reaction ID
ATP + acetyl-CoA + hydrogencarbonate = ADP + phosphate + malonyl-CoA non-ordered ter ter mechanism Zea mays
a

Source Tissue

Source Tissue Comment Organism Textmining
leaf 2 isoforms: non-mesophyll chloroplast form and mesophyll chloroplast form Zea mays
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + acetyl-CoA + HCO3-
-
 Zea mays ADP + phosphate + malonyl-CoA
-
 ?
ATP + acetyl-CoA + HCO3- key role in lipid metabolism Zea mays ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 220000, non-mesophyll chloroplast isoform, SDS-PAGE Zea mays
dimer 2 * 230000, mesophyll chloroplast isoform, SDS-PAGE Zea mays

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 non-mesophyll chloroplast isoform Zea mays
8 8.5 mesophyll chloroplast isoform Zea mays