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Literature summary for 6.4.1.1 extracted from

  • Rowan, A.N.; Newsholme, E.A.; Scrutton, M.C.
    Partial purification and some properties of pyruvate carboxylase from the flight muscle of the locust Schistocerca gregaria (1978), Biochim. Biophys. Acta, 522, 270-275.
    View publication on PubMed
Search for more literature for 6.4.1.1

Activating Compound

Activating Compound Comment Organism Structure
acetyl-CoA activates Rattus norvegicus
acetyl-CoA activates Schistocerca gregaria

Inhibitors

Inhibitors Comment Organism Structure
additional information insensitive to inhibition by di- and tricarboxylic acids Schistocerca gregaria

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.14
-
 ATP
-
 Schistocerca gregaria
0.19
-
 ATP
-
 Rattus norvegicus
0.24
-
 ATP pyruvate Rattus norvegicus
0.25
-
 pyruvate pyruvate Schistocerca gregaria
0.27
-
 HCO3- pyruvate Tenebrio molitor
0.32
-
 ATP
-
 Schistocerca gregaria
1.5
-
 HCO3-
-
 Tenebrio molitor
2.7
-
 HCO3-
-
 Rattus norvegicus
16.1
-
 HCO3-
-
 Schistocerca gregaria

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-
Schistocerca gregaria
-
-
-
Tenebrio molitor
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Schistocerca gregaria

Source Tissue

Source Tissue Comment Organism Textmining
flight muscle
-
 Schistocerca gregaria
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + pyruvate + HCO3-
-
 Rattus norvegicus ADP + phosphate + oxaloacetate
-
 ?
ATP + pyruvate + HCO3-
-
 Schistocerca gregaria ADP + phosphate + oxaloacetate
-
 ?
ATP + pyruvate + HCO3-
-
 Tenebrio molitor ADP + phosphate + oxaloacetate
-
 ?
ATP + pyruvate + HCO3- ATP in form of MgATP2- Rattus norvegicus ADP + phosphate + oxaloacetate
-
 ?
ATP + pyruvate + HCO3- ATP in form of MgATP2- Schistocerca gregaria ADP + phosphate + oxaloacetate
-
 ?