Activating Compound | Comment | Organism | Structure |
---|---|---|---|
acetyl-CoA | - |
Gallus gallus | |
acetyl-CoA | activates | Rattus norvegicus | |
acetyl-CoA | activates | Bacillus sp. (in: Bacteria) | |
acetyl-CoA | best activator | Bacillus sp. (in: Bacteria) | |
acetyl-CoA | in absence of acetyl-CoA the maximal rate of oxaloacetate synthesis is 20% of that obtained in presence of saturating concentrations of acetyl-CoA | Bacillus sp. (in: Bacteria) | |
acyl-CoA derivatives | activate | Bacillus sp. (in: Bacteria) | |
methanesulfonyl-CoA | activates | Saccharomyces cerevisiae | |
methanesulfonyl-CoA | activates | Bacillus sp. (in: Bacteria) | |
methanesulfonyl-CoA | inhibition | Gallus gallus | |
methanesulfonyl-CoA | inhibition | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-oxoglutarate | - |
Gallus gallus | |
2-oxoglutarate | - |
Rattus norvegicus | |
methanesulfonyl-CoA | activation | Bacillus sp. (in: Bacteria) | |
methanesulfonyl-CoA | - |
Gallus gallus | |
methanesulfonyl-CoA | - |
Rattus norvegicus | |
methanesulfonyl-CoA | activation | Saccharomyces cerevisiae | |
Trinitrobenzenesulfonate | inactivation of acetyl-CoA dependent activity, no effect on activator-independent activity | Bacillus sp. (in: Bacteria) | |
Trinitrobenzenesulfonate | - |
Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
16 | - |
HCO3- | with saturating concentrations of the activator acetyl-CoA | Bacillus sp. (in: Bacteria) | |
400 | - |
HCO3- | without acetyl-CoA | Bacillus sp. (in: Bacteria) |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus sp. (in: Bacteria) | - |
thermophilic | - |
Gallus gallus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Gallus gallus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + pyruvate + HCO3- | - |
Gallus gallus | ADP + phosphate + oxaloacetate | - |
? | |
ATP + pyruvate + HCO3- | - |
Rattus norvegicus | ADP + phosphate + oxaloacetate | - |
? | |
ATP + pyruvate + HCO3- | - |
Saccharomyces cerevisiae | ADP + phosphate + oxaloacetate | - |
? | |
ATP + pyruvate + HCO3- | - |
Bacillus sp. (in: Bacteria) | ADP + phosphate + oxaloacetate | - |
? |