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Literature summary for 6.3.5.9 extracted from
- The synthetase domains of cobalamin biosynthesis amidotransferases cobB and cobQ belong to a new family of ATP-dependent amidoligases, related to dethiobiotin synthetase (2000), Proteins, 41, 238-247.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 45000 | - |
2 * 45000 | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + hydrogenobyrinic acid + L-glutamine + H2O | Escherichia coli | vitamin B12 biosynthesis | ADP + phosphate + hydrogenobyrinic acid a,c-diamide + L-glutamate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + hydrogenobyrinic acid + L-glutamine + H2O | - |
Escherichia coli | ADP + phosphate + hydrogenobyrinic acid a,c-diamide + L-glutamate | - |
? | |
| ATP + hydrogenobyrinic acid + L-glutamine + H2O | vitamin B12 biosynthesis | Escherichia coli | ADP + phosphate + hydrogenobyrinic acid a,c-diamide + L-glutamate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 45000 | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cobalamin biosynthesis aminotransferase | - |
Escherichia coli |
| CobB | - |
Escherichia coli |
| cobyrinic acid a,c-diamide synthase | - |
Escherichia coli |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.3 | - |
- |
Escherichia coli |
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Release 2023.1 (January 2023)
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