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Literature summary for 6.3.5.9 extracted from

  • Crouzet, J.; Cauchois, L.; Blanche, F.; Debussche, L.; Thibaut, D.; Rouyez, M.C.; Rigault, S.; Mayaux, J.F.; Cameron, B.
    Nucleotide sequence of a Pseudomonas denitrificans 5.4-kilobase DNA fragment containing five cob genes and identification of structural genes encoding S-adenosyl-L-methionine: uroporphyrinogen III methyltransferase and cobyrinic acid a,c-diamide synthase (1990), J. Bacteriol., 172, 5968-5979.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
identification of the structural gene Pseudomonas denitrificans (nom. rej.)

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
2 * 45000, homodimer Pseudomonas denitrificans (nom. rej.)

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Pseudomonas denitrificans (nom. rej.) cobalamin biosynthetic pathway ?
-
?
additional information Pseudomonas denitrificans (nom. rej.) SC510 cobalamin biosynthetic pathway ?
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas denitrificans (nom. rej.) P21632
-
-
Pseudomonas denitrificans (nom. rej.) SC510 P21632
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Pseudomonas denitrificans (nom. rej.)

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + cobyrinic acid + L-glutamine + H2O
-
Pseudomonas denitrificans (nom. rej.) ADP + phosphate + cobyrinic acid a,c-diamide + L-glutamate
-
?
ATP + cobyrinic acid + L-glutamine + H2O
-
Pseudomonas denitrificans (nom. rej.) SC510 ADP + phosphate + cobyrinic acid a,c-diamide + L-glutamate
-
?
ATP + hydrogenobyrinic acid + L-glutamine + H2O amidation of carboxylic groups at positions a and c Pseudomonas denitrificans (nom. rej.) ADP + phosphate + hydrogenobyrinic acid a,c-diamide + L-glutamate
-
?
ATP + hydrogenobyrinic acid + L-glutamine + H2O amidation of carboxylic groups at positions a and c Pseudomonas denitrificans (nom. rej.) SC510 ADP + phosphate + hydrogenobyrinic acid a,c-diamide + L-glutamate
-
?
additional information cobalamin biosynthetic pathway Pseudomonas denitrificans (nom. rej.) ?
-
?
additional information cobalamin biosynthetic pathway Pseudomonas denitrificans (nom. rej.) SC510 ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 45000, homodimer Pseudomonas denitrificans (nom. rej.)

Synonyms

Synonyms Comment Organism
CobB
-
Pseudomonas denitrificans (nom. rej.)
cobyrinic acid a,c-diamide synthase
-
Pseudomonas denitrificans (nom. rej.)