Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.3.5.7 extracted from

  • Mailu, B.M.; Li, L.; Arthur, J.; Nelson, T.M.; Ramasamy, G.; Fritz-Wolf, K.; Becker, K.; Gardner, M.J.
    Plasmodium apicoplast Gln-tRNAGln biosynthesis utilizes a unique GatAB amidotransferase essential for erythrocytic stage parasites (2015), J. Biol. Chem., 290, 29629-29641 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
apicoplast in blood stage parasites, heterodimeric glutamyl-tRNA amidotransferase consisting of GatA and GatB subunits Plasmodium falciparum 20011
-
apicoplast in blood stage parasites, heterodimeric glutamyl-tRNA amidotransferase consisting of GatA and GatB subunits Plasmodium berghei 20011
-

Organism

Organism UniProt Comment Textmining
Plasmodium berghei A0A509AHQ9 and A0A509AM58 A0A077X9J8 i.e. subunit GatA, A0A077XDD6 i.e. subunit GatB
-
Plasmodium berghei ANKA A0A509AHQ9 and A0A509AM58 A0A077X9J8 i.e. subunit GatA, A0A077XDD6 i.e. subunit GatB
-
Plasmodium falciparum Q8I1S6 and C6KTC3 Q8I1S6 i.e. subunit GatA, C6KTC3 i.e. subunit GatB
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-glutamyl-tRNAGln + L-glutamine
-
Plasmodium falciparum ADP + phosphate + L-glutaminyl-tRNAGln + L-glutamate
-
?
ATP + L-glutamyl-tRNAGln + L-glutamine
-
Plasmodium berghei ADP + phosphate + L-glutaminyl-tRNAGln + L-glutamate
-
?
ATP + L-glutamyl-tRNAGln + L-glutamine
-
Plasmodium berghei ANKA ADP + phosphate + L-glutaminyl-tRNAGln + L-glutamate
-
?
additional information no substrate: L-glutamate Plasmodium falciparum ?
-
?
additional information no substrate: L-glutamate Plasmodium berghei ?
-
?
additional information no substrate: L-glutamate Plasmodium berghei ANKA ?
-
?

Subunits

Subunits Comment Organism
dimer 1 * 85000, subunit GatA, 1 * 94500, subunit GatB, SDS-PAGE Plasmodium falciparum

Synonyms

Synonyms Comment Organism
BANKA_112750 subunit GatB, gene name Plasmodium berghei
PBANKA_071810 subunit GatA, gene name Plasmodium berghei
PF3D7_0416100 subunit GatA, gene name Plasmodium falciparum
PF3D7_0628800 subunit GatB, gene name Plasmodium falciparum

General Information

General Information Comment Organism
physiological function gene encoding GatA is essential to the Plasmodium berghei blood stages Plasmodium berghei