Literature summary for 6.3.5.5 extracted from

Coxam, B.; Neyt, C.; Grassini, D.R.; Le Guen, L.; Smith, K.A.; Schulte-Merker, S.; Hogan, B.M.
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad) regulates Notch signaling and vascular development in zebrafish (2015), Dev. Dyn., 244, 1-9 .

Search for more literature for 6.3.5.5

Protein Variants

Protein Variants	Comment	Organism
P1850T	mutation affects a conserved residue in the linker region of Cad. Mutant animals display reduced lymphatic vessel development and hyperbranching arteries, reminiscent of Notch pathway mutants. Notch signaling is significantly reduced in the mutants	Danio rerio

Organism

Organism	UniProt	Comment	Textmining
Danio rerio	Q5EI67	trifunctional carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)