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Literature summary for 6.3.5.5 extracted from

  • Weber, G.; Reardon, M.
    Regulation of carbamoyl-phosphate synthase II (1986), Adv. Enzyme Regul., 25, 65-83.
    View publication on PubMed
Search for more literature for 6.3.5.5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.027
-
 L-Gln in presence of 10 mM ATP plus 15 mM MgCl2 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-Gln + HCO3- Rattus norvegicus important role of insulin in regulation of liver carbamoyl-phosphate synthase II and lack of responsiveness of the hepatoma enzyme to insulin concentration ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-
Morris hepatoma 3924A cell about 10fold higher activity than in normal liver Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ATP + L-Gln + HCO3-
-
 Rattus norvegicus 2 ADP + phosphate + L-Glu + carbamoyl phosphate
-
 ?
ATP + L-Gln + HCO3- important role of insulin in regulation of liver carbamoyl-phosphate synthase II and lack of responsiveness of the hepatoma enzyme to insulin concentration Rattus norvegicus ?
-
 ?