Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | addition of sugars to the plants, mainly glucose, induces the enzymes leading to the increased asparagine production | Phaseolus vulgaris |
Cloned (Comment) | Organism |
---|---|
gene NAS2, DNA and mino acid sequence determination and analysis, promoter determination, tissue expression analysis, overview | Phaseolus vulgaris |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | PvNAS2 is downregulated when carbon availability is reduced in nodules | Phaseolus vulgaris |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Phaseolus vulgaris |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-aspartate + L-glutamine + H2O | Phaseolus vulgaris | - |
AMP + diphosphate + L-asparagine + L-glutamate | - |
? | |
additional information | Phaseolus vulgaris | role for hexokinase in the sugar-sensing mechanism that regulates PvNAS2 expression in roots, downregulation of the asparagine synthetase enzyme and concomitantly asparagine production. Thereby a favourable environment is created for the efficient transfer of the amido group of glutamine for the synthesis of purines, and then ureide generation. | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Phaseolus vulgaris | - |
- |
- |
Phaseolus vulgaris | A9XS73 | cv. Negro Jamapa, gene NAS2 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
root | expression of PvNAS2 in roots is confined to vascular bundles and meristematic tissues, while in root nodules its expression is solely localized to vascular traces and outer cortical cells encompassing the central nitrogen-fixing zone, but never detected in either infected or non-infected cells located in the central region of the nodule | Phaseolus vulgaris | - |
root | high expression, confined to vascular bundles and meristematic tissues | Phaseolus vulgaris | - |
root nodule | expression of PvNAS2 in roots is confined to vascular bundles and meristematic tissues, while in root nodules its expression is solely localized to vascular traces and outer cortical cells encompassing the central nitrogen-fixing zone, but never detected in either infected or non-infected cells located in the central region of the nodule | Phaseolus vulgaris | - |
root nodule | mainly induced during the early days of nitrogen fixation, confined to vascular traces and outer cortical cells. Down-regulation when carbon availability is reduced, while the addition of sugars to the plants induces expression | Phaseolus vulgaris | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-aspartate + L-glutamine + H2O | - |
Phaseolus vulgaris | AMP + diphosphate + L-asparagine + L-glutamate | - |
? | |
additional information | role for hexokinase in the sugar-sensing mechanism that regulates PvNAS2 expression in roots, downregulation of the asparagine synthetase enzyme and concomitantly asparagine production. Thereby a favourable environment is created for the efficient transfer of the amido group of glutamine for the synthesis of purines, and then ureide generation. | Phaseolus vulgaris | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
asparagine amidotransferase | - |
Phaseolus vulgaris |
Asparagine synthetase | - |
Phaseolus vulgaris |
NAS2 | - |
Phaseolus vulgaris |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Phaseolus vulgaris |