Inhibitors | Comment | Organism | Structure |
---|---|---|---|
azaserine | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.1 | - |
L-Gln | - |
Rattus norvegicus | |
120 | - |
NH4+ | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | divalent metal ion required, Mg2+ more effective than Mn2+ | Rattus norvegicus | |
Mg2+ | Km: 23.7 | Rattus norvegicus | |
Mn2+ | at 2 mM 22.0% of the activity relative to Mg2+ | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Novikoff hepatoma cell | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-Asp + L-Gln | - |
Rattus norvegicus | AMP + diphosphate + Asn + Glu | - |
? | |
ATP + L-Asp + NH2OH | - |
Rattus norvegicus | AMP + diphosphate + beta-aspartylhydroxamate | - |
? | |
GTP + L-Asp + L-Gln | 5.6% of the activity relative to ATP | Rattus norvegicus | GMP + diphosphate + Asn + Glu | - |
? | |
additional information | the synthesis of Asn in mammalian tissues proceeds through the intermediate beta-aspartyladenylate | Rattus norvegicus | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.6 | 8 | - |
Rattus norvegicus |