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Literature summary for 6.3.5.4 extracted from
- The topology of the glutamine and ATP binding sites of human asparagine synthetase (1992), Arch. Biochem. Biophys., 299, 15-22.
General Stability
| General Stability | Organism |
|---|---|
| ATP protects from inactivation by UV irradiation in the presence of 8-N3ATP | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 6-diazo-5-oxo-L-norleucine | loss of Gln-dependent reactions, but no effect on ATP binding as measured during amminoa-dependent Asn synthesis | Homo sapiens |  |
| 8-N3ATP | loss of NH4+-dependent Asn synthesis, but no effect on the glutaminase activity | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-Asp + L-Gln | - |
Homo sapiens | AMP + diphosphate + Asn + Glu | - |
? | |
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Release 2023.1 (January 2023)
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