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Literature summary for 6.3.5.4 extracted from
- Mapping the Asp binding site of Escherichia coli asparagine synthetase B using substrate analogs (1996), J. Med. Chem., 39, 2367-2378.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5'-O-[p-(fluorosulfonyl)benzoyl]adenosine | covalently modifies the enzyme | Escherichia coli |  |
| aspartic acid analogs | - |
Escherichia coli | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
Asn synthetase B | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-Asp + L-Gln | - |
Escherichia coli | AMP + diphosphate + Asn + Glu | - |
? | |
| additional information | enzyme is extremly selective, being able to discriminate between metabolites that have similar structures to Asp | Escherichia coli | ? | - |
? | |
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