Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.3.5.3 extracted from

  • Buchanan, J.M.
    Covalent reaction of substrates and antimetabolites with formylglycinamide ribonucleotide amidotransferase (1982), Methods Enzymol., 87, 76-84.
    View publication on PubMed
Search for more literature for 6.3.5.3

Inhibitors

Inhibitors Comment Organism Structure
6-diazo-5-oxo-L-norleucine
-
 Gallus gallus
albizziin
-
 Gallus gallus
iodoacetamide
-
 Gallus gallus
iodoacetate
-
 Gallus gallus
O-diazoacetyl-L-Ser
-
 Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine + L-glutamate substrates add sequentially to form a quarternary complex. Gln adds first with ATP and 5'-phosphoribosylformylglycinamide adding subsequently Gallus gallus
a

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 5'-phosphoribosylformylglycinamide + L-Gln + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + phosphate + 5'-phosphoribosylformylglycinamidine + L-Glu
-
 ?
ATP + 5'-phosphoribosylformylglycinamide + L-Gln + H2O
-
 Gallus gallus ADP + phosphate + 5'-phosphoribosylformylglycinamidine + L-Glu
-
 ?