BRENDA - Enzyme Database
show all sequences of 6.3.5.10

Biosynthesis of vitamin B12: stepwise amidation of carboxyl groups b, d, e, and g of cobyrinic acid a,c-diamide is catalyzed by one enzyme in Pseudomonas denitrificans

Blanche, F.; Couder, M.; Debussche, L.; Thibaut, D.; Cameron, B.; Cruzet, J.; J. Bacteriol. 173, 6046-6051 (1991)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
cobQ gene
Pseudomonas denitrificans (nomen rejiciendum)
General Stability
General Stability
Organism
20% w/v and 1 mM dithiothreitol are necessary to stabilize enzyme during purification
Pseudomonas denitrificans (nomen rejiciendum)
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
-
Pseudomonas denitrificans (nomen rejiciendum)
0.00104
-
adenosylcobyrinic acid a,c-diamide
pH 7.5
Pseudomonas denitrificans (nomen rejiciendum)
0.00121
-
adenosylcobyrinic acid tetraamide
pH 7.5
Pseudomonas denitrificans (nomen rejiciendum)
0.00122
-
adenosylcobyrinic acid triamide
pH 7.5
Pseudomonas denitrificans (nomen rejiciendum)
0.00125
-
adenosylcobyrinic acid pentaamide
pH 7.5
Pseudomonas denitrificans (nomen rejiciendum)
0.011
-
ATP
pH 7.5, adenosylcobyrinic acid a,c-diamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.033
-
L-glutamine
pH 7.5, adenosylcobyrinic acid triamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.035
-
ATP
pH 7.5, adenosylcobyrinic acid triamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.045
-
L-glutamine
pH 7.5, adenosylcobyrinic acid a,c-diamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.049
-
L-glutamine
pH 7.5, adenosylcobyrinic acid pentaamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.064
-
L-glutamine
pH 7.5, adenosylcobyrinic acid tetraamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.088
-
ATP
pH 7.5, adenosylcobyrinic acid pentaamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.12
-
ATP
pH 7.5, adenosylcobyrinic acid tetraamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
20.4
-
ammonia
pH 7.5, adenosylcobyrinic acid a,c-diamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mg2+
Mg2+-dependent
Pseudomonas denitrificans (nomen rejiciendum)
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
52000
-
predicted from DNA sequence of the cobQ gene
Pseudomonas denitrificans (nomen rejiciendum)
57000
-
2 * 57000, SDS-PAGE
Pseudomonas denitrificans (nomen rejiciendum)
97300
-
gel filtration
Pseudomonas denitrificans (nomen rejiciendum)
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
Pseudomonas denitrificans (nomen rejiciendum)
biosynthesis of vitamin B12, cobalamin biosynthetic pathway
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
biosynthesis of vitamin B12, cobalamin biosynthetic pathway
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pseudomonas denitrificans (nomen rejiciendum)
-
; recombinant strain SC510 Rifr(pXL617)
-
Oxidation Stability
Oxidation Stability
Organism
sensitive to oxidation
Pseudomonas denitrificans (nomen rejiciendum)
Purification (Commentary)
Commentary
Organism
45fold
Pseudomonas denitrificans (nomen rejiciendum)
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.083
-
pH 7.5, adenosylcobyrinic acid a,c-diamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
Storage Stability
Storage Stability
Organism
-20°C or 0°C, purified enzyme, 0.1 M Tris hydrochloride, pH 7.5, 48 h, 100% loss of activity
Pseudomonas denitrificans (nomen rejiciendum)
-20°C, purified enzyme, 50 mM Tris hydrochloride, pH 7.5, 0.1 M sodium chloride, 1 mM dithiothreitol, 20% glycerol, several weeks, stable
Pseudomonas denitrificans (nomen rejiciendum)
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
adenosylcobyrinic acid a,c-diamide + ATP + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
adenosylcobyric acid + ADP + phosphate + L-glutamate
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
?
adenosylcobyrinic acid a,c-diamide + ATP + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
adenosylcobyric acid + ADP + phosphate + L-glutamate
-
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
?
ATP + adenosylcobyrinic acid a,c-diamide + ammonia + H2O
ammonia can replace L-glutamine as amide group donor, but L-glutamine is preferred
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + ?
-
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
biosynthesis of vitamin B12, cobalamin biosynthetic pathway
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
enzyme catalyzes the stepwise amidation of carboxyl groups b, d, e, and g of cobyrinic acid a,c-diamide, four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of corbyrinic acid triamide, tetraamide, and pentaamide intermediates, the amidations are carried out in a specific order, enzyme is specific to coenzyme forms of substrates, no amidation of the carboxyl group at position f, L-glutamine is the preferred amide group donor
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
biosynthesis of vitamin B12, cobalamin biosynthetic pathway
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
enzyme catalyzes the stepwise amidation of carboxyl groups b, d, e, and g of cobyrinic acid a,c-diamide, four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of corbyrinic acid triamide, tetraamide, and pentaamide intermediates, the amidations are carried out in a specific order, enzyme is specific to coenzyme forms of substrates, no amidation of the carboxyl group at position f, L-glutamine is the preferred amide group donor
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid pentaamide + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid tetraamide + L-glutamine + H2O
two-step amidation
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid triamide + L-glutamine + H2O
three-step amidation
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
cobinic acid a,c-diamide + ATP + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
cobinamide + ADP + phosphate + L-glutamate
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
?
cobinic acid a,c-diamide + ATP + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
cobinamide + ADP + phosphate + L-glutamate
-
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
?
additional information
no amidation of adenosylcobyric acid, hydrogenobyrinic acid a,c-diamide, monocyano or diaqua form of cobyrinic acid a,c-diamide
651618
Pseudomonas denitrificans (nomen rejiciendum)
?
-
-
-
-
additional information
no amidation of adenosylcobyric acid, hydrogenobyrinic acid a,c-diamide, monocyano or diaqua form of cobyrinic acid a,c-diamide
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
?
-
-
-
-
Subunits
Subunits
Commentary
Organism
dimer
2 * 57000, SDS-PAGE
Pseudomonas denitrificans (nomen rejiciendum)
homodimer
2 * 57000, SDS-PAGE
Pseudomonas denitrificans (nomen rejiciendum)
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
-
broad pH-optimum around
Pseudomonas denitrificans (nomen rejiciendum)
Cofactor
Cofactor
Commentary
Organism
Structure
ATP
ATP-dependent
Pseudomonas denitrificans (nomen rejiciendum)
pI Value
Organism
Commentary
pI Value Maximum
pI Value
Pseudomonas denitrificans (nomen rejiciendum)
isoelectric focusing
-
6
Cloned(Commentary) (protein specific)
Commentary
Organism
cobQ gene
Pseudomonas denitrificans (nomen rejiciendum)
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
ATP
ATP-dependent
Pseudomonas denitrificans (nomen rejiciendum)
General Stability (protein specific)
General Stability
Organism
20% w/v and 1 mM dithiothreitol are necessary to stabilize enzyme during purification
Pseudomonas denitrificans (nomen rejiciendum)
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
-
Pseudomonas denitrificans (nomen rejiciendum)
0.00104
-
adenosylcobyrinic acid a,c-diamide
pH 7.5
Pseudomonas denitrificans (nomen rejiciendum)
0.00121
-
adenosylcobyrinic acid tetraamide
pH 7.5
Pseudomonas denitrificans (nomen rejiciendum)
0.00122
-
adenosylcobyrinic acid triamide
pH 7.5
Pseudomonas denitrificans (nomen rejiciendum)
0.00125
-
adenosylcobyrinic acid pentaamide
pH 7.5
Pseudomonas denitrificans (nomen rejiciendum)
0.011
-
ATP
pH 7.5, adenosylcobyrinic acid a,c-diamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.033
-
L-glutamine
pH 7.5, adenosylcobyrinic acid triamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.035
-
ATP
pH 7.5, adenosylcobyrinic acid triamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.045
-
L-glutamine
pH 7.5, adenosylcobyrinic acid a,c-diamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.049
-
L-glutamine
pH 7.5, adenosylcobyrinic acid pentaamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.064
-
L-glutamine
pH 7.5, adenosylcobyrinic acid tetraamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.088
-
ATP
pH 7.5, adenosylcobyrinic acid pentaamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
0.12
-
ATP
pH 7.5, adenosylcobyrinic acid tetraamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
20.4
-
ammonia
pH 7.5, adenosylcobyrinic acid a,c-diamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mg2+
Mg2+-dependent
Pseudomonas denitrificans (nomen rejiciendum)
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
52000
-
predicted from DNA sequence of the cobQ gene
Pseudomonas denitrificans (nomen rejiciendum)
57000
-
2 * 57000, SDS-PAGE
Pseudomonas denitrificans (nomen rejiciendum)
97300
-
gel filtration
Pseudomonas denitrificans (nomen rejiciendum)
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
Pseudomonas denitrificans (nomen rejiciendum)
biosynthesis of vitamin B12, cobalamin biosynthetic pathway
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
biosynthesis of vitamin B12, cobalamin biosynthetic pathway
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
?
Oxidation Stability (protein specific)
Oxidation Stability
Organism
sensitive to oxidation
Pseudomonas denitrificans (nomen rejiciendum)
Purification (Commentary) (protein specific)
Commentary
Organism
45fold
Pseudomonas denitrificans (nomen rejiciendum)
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.083
-
pH 7.5, adenosylcobyrinic acid a,c-diamide as substrate
Pseudomonas denitrificans (nomen rejiciendum)
Storage Stability (protein specific)
Storage Stability
Organism
-20°C or 0°C, purified enzyme, 0.1 M Tris hydrochloride, pH 7.5, 48 h, 100% loss of activity
Pseudomonas denitrificans (nomen rejiciendum)
-20°C, purified enzyme, 50 mM Tris hydrochloride, pH 7.5, 0.1 M sodium chloride, 1 mM dithiothreitol, 20% glycerol, several weeks, stable
Pseudomonas denitrificans (nomen rejiciendum)
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
adenosylcobyrinic acid a,c-diamide + ATP + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
adenosylcobyric acid + ADP + phosphate + L-glutamate
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
?
adenosylcobyrinic acid a,c-diamide + ATP + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
adenosylcobyric acid + ADP + phosphate + L-glutamate
-
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
?
ATP + adenosylcobyrinic acid a,c-diamide + ammonia + H2O
ammonia can replace L-glutamine as amide group donor, but L-glutamine is preferred
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + ?
-
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
biosynthesis of vitamin B12, cobalamin biosynthetic pathway
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
enzyme catalyzes the stepwise amidation of carboxyl groups b, d, e, and g of cobyrinic acid a,c-diamide, four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of corbyrinic acid triamide, tetraamide, and pentaamide intermediates, the amidations are carried out in a specific order, enzyme is specific to coenzyme forms of substrates, no amidation of the carboxyl group at position f, L-glutamine is the preferred amide group donor
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
biosynthesis of vitamin B12, cobalamin biosynthetic pathway
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O
enzyme catalyzes the stepwise amidation of carboxyl groups b, d, e, and g of cobyrinic acid a,c-diamide, four-step amidation sequence from cobyrinic acid a,c-diamide to cobyric acid via the formation of corbyrinic acid triamide, tetraamide, and pentaamide intermediates, the amidations are carried out in a specific order, enzyme is specific to coenzyme forms of substrates, no amidation of the carboxyl group at position f, L-glutamine is the preferred amide group donor
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid pentaamide + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid tetraamide + L-glutamine + H2O
two-step amidation
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
ATP + adenosylcobyrinic acid triamide + L-glutamine + H2O
three-step amidation
651618
Pseudomonas denitrificans (nomen rejiciendum)
ADP + phosphate + adenosylcobyric acid + L-glutamate
-
-
-
?
cobinic acid a,c-diamide + ATP + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
cobinamide + ADP + phosphate + L-glutamate
-
651618
Pseudomonas denitrificans (nomen rejiciendum)
?
cobinic acid a,c-diamide + ATP + L-glutamine + H2O
-
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
cobinamide + ADP + phosphate + L-glutamate
-
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
?
additional information
no amidation of adenosylcobyric acid, hydrogenobyrinic acid a,c-diamide, monocyano or diaqua form of cobyrinic acid a,c-diamide
651618
Pseudomonas denitrificans (nomen rejiciendum)
?
-
-
-
-
additional information
no amidation of adenosylcobyric acid, hydrogenobyrinic acid a,c-diamide, monocyano or diaqua form of cobyrinic acid a,c-diamide
651618
Pseudomonas denitrificans (nomen rejiciendum) SC510 RifT
?
-
-
-
-
Subunits (protein specific)
Subunits
Commentary
Organism
dimer
2 * 57000, SDS-PAGE
Pseudomonas denitrificans (nomen rejiciendum)
homodimer
2 * 57000, SDS-PAGE
Pseudomonas denitrificans (nomen rejiciendum)
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
-
broad pH-optimum around
Pseudomonas denitrificans (nomen rejiciendum)
pI Value (protein specific)
Organism
Commentary
pI Value Maximum
pI Value
Pseudomonas denitrificans (nomen rejiciendum)
isoelectric focusing
-
6
Other publictions for EC 6.3.5.10
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
674206
Williams
The multiple amidation reactio ...
Salmonella enterica subsp. enterica serovar Typhimurium
J. Am. Chem. Soc.
129
294-295
2007
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1
4
-
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-
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2
-
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4
-
-
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4
-
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1
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1
1
4
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4
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4
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-
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-
655868
Woodson
A new pathway for salvaging th ...
Halobacterium sp., Salmonella enterica, Salmonella enterica TR6583
J. Bacteriol.
185
7193-7201
2003
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-
2
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2
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4
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3
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8
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2
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2
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4
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8
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644278
Warren
The biosynthesis of adenosylco ...
Pseudomonas denitrificans (nomen rejiciendum), Salmonella enterica
Nat. Prod. Rep.
19
390-412
2002
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1
2
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2
-
-
-
-
-
-
-
-
4
1
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
653832
Galperin
The synthetase domains of coba ...
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238-247
2000
-
-
-
-
-
-
-
1
-
1
2
2
-
5
-
-
-
1
-
-
-
-
4
2
-
-
-
-
2
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
2
2
-
-
-
-
-
-
-
-
4
2
-
-
-
-
2
-
-
-
-
-
-
-
-
-
644281
Blanche F.; Maton
Purification and characterizat ...
Pseudomonas denitrificans (nomen rejiciendum)
J. Bacteriol.
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7452-7454
1992
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
636869
Crouzet
Nucleotide sequence and geneti ...
Pseudomonas denitrificans (nomen rejiciendum), Pseudomonas denitrificans (nomen rejiciendum) SC510 Rifr(pXL617)
J. Bacteriol.
173
6074-6087
1991
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-
1
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-
-
-
-
-
-
2
2
-
4
-
-
1
-
-
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
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-
2
2
-
-
-
1
-
-
-
-
4
1
-
-
-
-
-
-
-
-
-
-
-
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-
-
651618
Blanche
Biosynthesis of vitamin B12: s ...
Pseudomonas denitrificans (nomen rejiciendum)
J. Bacteriol.
173
6046-6051
1991
-
-
1
-
-
1
-
14
-
1
3
2
-
1
1
-
1
-
-
-
1
2
14
2
-
-
-
-
1
-
-
1
-
1
-
-
-
1
1
-
-
1
-
-
-
14
-
1
3
2
-
1
-
1
-
-
1
2
14
2
-
-
-
-
1
-
-
1
-
-
-
-
-
-