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Literature summary for 6.3.5.10 extracted from

  • Crouzet, J.; Levy-Schil, S.; Cameron, B.; Cauchois, L.; Rigault, S.; Rouyez, M.C.; Blanche, F.; Debussche, L.; Thibaut, D.
    Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair Pseudomonas denitrificans DNA fragment containing five cob genes and identification of structural genes encoding Cob(I)alamin adenosyltransferase, cobyric acid synthase, and bifunctional cobinamide kinase-cobinamide phosphate guanylyltransferase (1991), J. Bacteriol., 173, 6074-6087.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
cobQ gene, sequencing, genomic organization Pseudomonas denitrificans (nom. rej.)

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
51982
-
 2 * 51982, CobQ sequence calculation, 2 * 57000 Pseudomonas denitrificans (nom. rej.)
57000
-
 2 * 51982, CobQ sequence calculation, 2 * 57000 Pseudomonas denitrificans (nom. rej.)

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Pseudomonas denitrificans (nom. rej.) cobalamin biosynthetic pathway, involved in coenzyme B12 synthesis ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O Pseudomonas denitrificans (nom. rej.) SC510 Rifr(pXL617) cobalamin biosynthetic pathway, involved in coenzyme B12 synthesis ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas denitrificans (nom. rej.) P29932
-
-
Pseudomonas denitrificans (nom. rej.) SC510 Rifr(pXL617) P29932
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pseudomonas denitrificans (nom. rej.)

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O cobalamin biosynthetic pathway, involved in coenzyme B12 synthesis Pseudomonas denitrificans (nom. rej.) ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O CobQ catalyzes amidations at positions b, d, e and g Pseudomonas denitrificans (nom. rej.) ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O cobalamin biosynthetic pathway, involved in coenzyme B12 synthesis Pseudomonas denitrificans (nom. rej.) SC510 Rifr(pXL617) ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?
ATP + adenosylcobyrinic acid a,c-diamide + L-glutamine + H2O CobQ catalyzes amidations at positions b, d, e and g Pseudomonas denitrificans (nom. rej.) SC510 Rifr(pXL617) ADP + phosphate + adenosylcobyric acid + L-glutamate
-
 ?

Subunits

Subunits Comment Organism
homodimer 2 * 51982, CobQ sequence calculation, 2 * 57000 Pseudomonas denitrificans (nom. rej.)