Literature summary for 6.3.4.5 extracted from

Chng, Y.R.; Ong, J.L.; Ching, B.; Chen, X.L.; Wong, W.P.; Chew, S.F.; Ip, Y.K.
Molecular characterization of argininosuccinate synthase and argininosuccinate lyase from the liver of the African lungfish Protopterus annectens, and their mRNA expression levels in the liver, kidney, brain and skeletal muscle during aestivation (2014), J. Comp. Physiol. B, 184, 835-853 .

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Organism

Organism	UniProt	Comment	Textmining
Protopterus annectens	S4V5K7	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	changes in Ass and Asl mRNA expression levels during the three phases of aestivation can be related to the supply of arginine for NO synthesis	Protopterus annectens	-
kidney	significant decrease in Ass mRNA expression level after 6 months of aestivation	Protopterus annectens	-
liver	strong expression of both argininosuccinate synthase and argininosuccinate lyase. mRNA expression levels of Ass and Asl increase significantly during the induction phase of aestivation	Protopterus annectens	-
skeletal muscle	decrease in Ass mRNA expression level during aestivation, accompanied with decreases in the concentrations of arginine and NO	Protopterus annectens	-

Synonyms

Synonyms	Comment	Organism
ASS	-	Protopterus annectens

Expression

Organism	Comment	Expression
Protopterus annectens	in the kidney, there is a significant decrease in ass mRNA expression level after 6 months of aestivation. In skeletal muscle, Ass mRNA expression decreases during aestivation	down
Protopterus annectens	in the brain, changes in Ass and asl mRNA expression levels during the three phases of aestivation can be related to the supply of arginine for NO synthesis in response to conditions that resemble ischaemia and ischaemia-reperfusion during the maintenance and arousal phase of aestivation, respectively	additional information
Protopterus annectens	in liver, mRNA expression levels of Ass and Asl increase significantly during the induction phase of aestivation	up

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Release 2023.1 (January 2023)