Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium perfringens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
FHS | - |
Clostridium perfringens |
General Information | Comment | Organism |
---|---|---|
physiological function | in Escherichia coli, the essential function of folD can be replaced by Clostridium perfringens Fhs. The Fhs-supported folD deletion strains grow well in a complex medium and require purines and glycine as supplements for growth in M9 minimal medium. The in vivo levels of N10-formyltetrahydrofolate in the folD deletion strain carrying plasmid-borne Fhs are limiting. The folD deletion strain carrying harboring Fhs on the chromosome shows a high NADP+-to-NADPH ratio and hypersensitivity to trimethoprim | Clostridium perfringens |