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Literature summary for 6.3.4.3 extracted from

  • Radfar, R.; Shin, R.; Sheldrick, G.M.; Minor, W.; Lovell, C.R.; Odom, J.D.; Dunlap, R.B.; Lebioda, L.
    The crystal structure of N(10)-formyltetrahydrofolate synthetase from Moorella thermoacetica (2000), Biochemistry, 39, 3920-3926.
    View publication on PubMed
Search for more literature for 6.3.4.3

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Moorella thermoacetica

Crystallization (Commentary)

Crystallization (Comment) Organism
Se-Met FTHFS is crystallized by hanging-drop vapor-diffusion, crystals diffract to 2.5 A Moorella thermoacetica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + formate + tetrahydrofolate Moorella thermoacetica
-
 ADP + phosphate + 10-formyltetrahydrofolate
-
 ?

Organism

Organism UniProt Comment Textmining
Moorella thermoacetica P21164 previously referred to as Clostridium thermoaceticum
-

Purification (Commentary)

Purification (Comment) Organism
recombinant FTHFS, heparin Agarose, Phenyl Sepharose Moorella thermoacetica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + formate + tetrahydrofolate
-
 Moorella thermoacetica ADP + phosphate + 10-formyltetrahydrofolate
-
 ?

Synonyms

Synonyms Comment Organism
FTHFS
-
 Moorella thermoacetica