Crystallization (Comment) | Organism |
---|---|
structure of apo-PurZ at 1.3 A resolution and structures in complex with ATP, with dGMP, ATP, and Mg2+, and with beta,gamma-methyleneadenosine 5'-triphosphate, dGMP, and aspartate | Vibrio phage phiVC8 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
cyanophage S-2L | - |
- |
- |
Vibrio phage phiVC8 | G3FFN6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + dGMP + L-aspartate | - |
Vibrio phage phiVC8 | ADP + phosphate + 2-amino-2'-deoxy-N6-[(2S)-succino]adenylate | - |
? | |
ATP + dGMP + L-aspartate | - |
cyanophage S-2L | ADP + phosphate + 2-amino-2'-deoxy-N6-[(2S)-succino]adenylate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Adenylosuccinate synthetase | - |
Vibrio phage phiVC8 |
phiVC8_p27 | - |
Vibrio phage phiVC8 |
purZ | - |
Vibrio phage phiVC8 |
General Information | Comment | Organism |
---|---|---|
physiological function | cyanophage S-2L and Vibrio phage PhiVC8 encode a third purine pathway catalyzed by PurZ. PurZ condenses aspartate with deoxyguanylate into dSMP (N6-succino-2-amino-2'-deoxyadenylate), which undergoes defumarylation and phosphorylation to give dZTP (2-amino-2'-deoxyadenosine-5'-triphosphate), a substrate for the phage DNA polymerase | Vibrio phage phiVC8 |
physiological function | cyanophage S-2L and Vibrio phage PhiVC8 encode a third purine pathway catalyzed by PurZ. PurZ condenses aspartate with deoxyguanylate into dSMP (N6-succino-2-amino-2'-deoxyadenylate), which undergoes defumarylation and phosphorylation to give dZTP (2-amino-2'-deoxyadenosine-5'-triphosphate), a substrate for the phage DNA polymerase | cyanophage S-2L |