Literature summary for 6.3.4.2 extracted from

Li, X.; Xie, J.; Hei, M.; Tang, J.; Wang, Y.; Foerster, E.; Zhao, S.
High level of CTP synthase induces formation of cytoophidia in cortical neurons and impairs corticogenesis (2018), Histochem. Cell Biol., 149, 61-73 .

Search for more literature for 6.3.4.2

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	embryonic brain	Mus musculus	-
embryo	embryonic brain	Mus musculus	-

General Information

General Information	Comment	Organism
physiological function	overexpression of CTPS by in utero electroporation in the embryonic mouse brain induces formation of cytoophidia in developing cortical neurons and impairs neuronal migration. The increase of cytoophidia accelerates neuronal differentiation and inhibits neural progenitor cell proliferation by reducing their mitotic activity. The cytoophidia diffuse during the early G1-phase of the cell cycle	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)