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Literature summary for 6.3.4.2 extracted from
- CTP synthetase from Ehrlich ascites tumor cells. Subunit stoichiometry and regulation of activity (1985), Biochim. Biophys. Acta, 829, 34-43.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| GDP | slight activation | Mus musculus |  |
| GMP | slight activation | Mus musculus | |
| GTP | activates glutamine reaction, no activation of ammonia reaction | Mus musculus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CTP | mixed inhibition | Mus musculus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | absolutely dependent on | Mus musculus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 66000 | - |
2 * 66000, SDS-PAGE | Mus musculus |
| 122000 | - |
sucrose density gradient centrifugation | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + UTP + NH4+ | - |
Mus musculus | ADP + phosphate + CTP | - |
? | |
| deoxyATP + UTP + NH4+ | - |
Mus musculus | deoxyADP + phosphate + CTP | - |
? | |
| deoxyGTP + UTP + NH4+ | - |
Mus musculus | deoxyGDP + phosphate + CTP | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 66000, SDS-PAGE | Mus musculus |
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