Literature summary for 6.3.4.13 extracted from

Daubner, S.C.; Young, M.; Sammons, R.D.; Courtney, L.F.; Benkovic, S.J.
Structural and mechanistic studies on the HeLa and chicken liver proteins that catalyze glycinamide ribonucleotide synthesis and formylation and aminoimidazole ribonucleotide synthesis (1986), Biochemistry, 25, 2951-2957.

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Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
112000	-	x * 112000, enzyme protein with glycinamide phosphoribosylamine-glycine ligase and aminoimidazole ribonucleotide synthetase activity, SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Gallus gallus	-	-	-
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
copurification of phosphoribosylamine-glycine ligase and aminoimidazole ribonucleotide synthetase	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
HeLa cell	-	Homo sapiens	-
liver	-	Gallus gallus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.228	-	-	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 5-phosphoribosylamine + Gly	-	Gallus gallus	ADP + phosphate + 5-phosphoribosylglycinamide	-	?
ATP + 5-phosphoribosylamine + Gly	-	Homo sapiens	ADP + phosphate + 5-phosphoribosylglycinamide	-	?

Subunits

Subunits	Comment	Organism
?	-	Gallus gallus
?	x * 112000, enzyme protein with glycinamide phosphoribosylamine-glycine ligase and aminoimidazole ribonucleotide synthetase activity, SDS-PAGE	Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
additional information	-	additional information	-	Gallus gallus
additional information	-	additional information	-	Homo sapiens

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Release 2023.1 (January 2023)