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Literature summary for 6.3.3.3 extracted from

  • Izumi, Y.; Tani, Y.; Ogata, K.
    Microbiological biosynthesis of biotin (1979), Methods Enzymol., 62, 326-338.
    View publication on PubMed
Search for more literature for 6.3.3.3

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
 Pseudomonas graveolens
2,2'-dipyridyl
-
 Pseudomonas graveolens
7,8-diaminononanoate competitive to diaminobiotin Pseudomonas graveolens
ADP competitive to ATP Pseudomonas graveolens
Diaminobiotin competitive to 7,8-diaminononanoate Pseudomonas graveolens
EDTA
-
 Pseudomonas graveolens

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ 71-91% of the activity relative to Mg2+ Pseudomonas graveolens
Mg2+ required Pseudomonas graveolens
Mn2+ 95-136% of the activity relative to Mg2+ Pseudomonas graveolens

Organism

Organism UniProt Comment Textmining
Pseudomonas graveolens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pseudomonas graveolens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 7,8-diaminononanoate + CO2
-
 Pseudomonas graveolens ADP + phosphate + dethiobiotin
-
 ?
ATP + diaminobiotin + CO2
-
 Pseudomonas graveolens ADP + phosphate + biotin
-
 ?
CTP + 7,8-diaminononanoate + CO2
-
 Pseudomonas graveolens CDP + phosphate + dethiobiotin
-
 ?
GTP + 7,8-diaminononanoate + CO2
-
 Pseudomonas graveolens GDP + phosphate + dethiobiotin
-
 ?
ITP + 7,8-diaminononanoate + CO2
-
 Pseudomonas graveolens IDP + phosphate + dethiobiotin
-
 ?
UTP + 7,8-diaminononanoate + CO2
-
 Pseudomonas graveolens UDP + phosphate + dethiobiotin
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
50 55
-
 Pseudomonas graveolens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 8
-
 Pseudomonas graveolens