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Literature summary for 6.3.2.61 extracted from

  • Janke, C.; Rogowski, K.; Wloga, D.; Regnard, C.; Kajava, A.V.; Strub, J.M.; Temurak, N.; van Dijk, J.; Boucher, D.; van Dorsselaer, A.; Suryavanshi, S.; Gaertig, J.; Edde, B.
    Tubulin polyglutamylase enzymes are members of the TTL domain protein family (2005), Science, 308, 1758-1762 .
    View publication on PubMed
Search for more literature for 6.3.2.61

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
n ATP + [alpha-tubulin]-L-glutamate + n L-glutamate Mus musculus overall reaction [alpha-tubulin]-(gamma-(poly-alpha-L-glutamyl)-L-glutamyl)-L-glutamate + n ADP + n phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
n ATP + [alpha-tubulin]-L-glutamate + n L-glutamate overall reaction Mus musculus [alpha-tubulin]-(gamma-(poly-alpha-L-glutamyl)-L-glutamyl)-L-glutamate + n ADP + n phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 49000, calculated from amino acid sequence Mus musculus

Synonyms

Synonyms Comment Organism
neuronal tubulin polyglutamylase
-
 Mus musculus
TTLL1 catalytic subunit of neural tubulin polyglutamylase Mus musculus
tubulin tyrosine ligase-like protein 1
-
 Mus musculus