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Literature summary for 6.3.2.61 extracted from
- Tubulin polyglutamylation stimulates spastin-mediated microtubule severing (2010), J. Cell Biol., 189, 945-954.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HeLa cells or U2OS cells | Mus musculus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| E439A | inactive mutant of isoform TTLL6 | Mus musculus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 10 mM used in assay conditions | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TTLL1 | isoform | Mus musculus |
| ttll6 | isoform | Mus musculus |
| tubulin tyrosine ligase like | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | enzyme-meditated glutamylation of tubulin directly stimulates spastin-mediated severing of microtubules | Mus musculus |
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