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Literature summary for 6.3.2.61 extracted from

  • Pathak, N.; Austin, C.A.; Drummond, I.A.
    Tubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility (2011), J. Biol. Chem., 286, 11685-11695 .
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cilium
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Danio rerio 5929
-

Organism

Organism UniProt Comment Textmining
Danio rerio A8CVX7 wild type TuAB and CD-41 GFP zebrafish lines
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Synonyms

Synonyms Comment Organism
ttll6
-
Danio rerio

General Information

General Information Comment Organism
malfunction knockdown of ttll6 strongly reduces cilia tubulin glutamylation but only partially affects cilia structure and motility. Combined loss of function of ttll3 and ttll6 causes near complete loss of cilia motility and induced a variety of axonemal ultrastructural defects Danio rerio