Literature summary for 6.3.2.54 extracted from

Dale, S.E.; Doherty-Kirby, A.; Lajoie, G.; Heinrichs, D.E.
Role of siderophore biosynthesis in virulence of Staphylococcus aureus identification and characterization of genes involved in production of a siderophore (2004), Infect. Immun., 72, 29-37 .

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Organism

Organism	UniProt	Comment	Textmining
Staphylococcus aureus	Q2G1M9	-	-
Staphylococcus aureus NCTC 8325	Q2G1M9	-	-

Synonyms

Synonyms	Comment	Organism
sbnE	-	Staphylococcus aureus

General Information

General Information	Comment	Organism
physiological function	enzyme is involved in biosynthesis of staphyloferrin B, which is required when cells are starved for iron. Mutation of the SbnE gene eliminates the ability to produce staphyloferrin B under iron-limited growth conditions. SbnE mutants display a drastic growth deficiency, compared to the wild-type, in iron-restricted growth medium, whereas no such deficiency is observed during growth in iron-repleted medium. The SbnE mutant is compromised in a murine kidney abscess model of Staphylococcus aureus infection	Staphylococcus aureus

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Release 2023.1 (January 2023)