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BRENDA support

Literature summary for 6.3.2.51 extracted from

  • Bosveld, F.; Rana, A.; Lemstra, W.; Kampinga, H.H.; Sibon, O.C.
    Drosophila phosphopantothenoylcysteine synthetase is required for tissue morphogenesis during oogenesis (2008), BMC Res. Notes, 1, 75.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + (R)-4'-phosphopantothenate + L-cysteine Drosophila melanogaster
-
AMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
egg
-
Drosophila melanogaster
-
oocyte
-
Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (R)-4'-phosphopantothenate + L-cysteine
-
Drosophila melanogaster AMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine
-
?

Synonyms

Synonyms Comment Organism
PPCS
-
Drosophila melanogaster

General Information

General Information Comment Organism
malfunction enzyme mutations disrupt female fecundity, affect egg chamber development, and also induce alterations in scutellar patterning and cause wing vein abnormalities Drosophila melanogaster
physiological function the enzyme is required for various processes that occur during oogenesis including chorion patterning Drosophila melanogaster