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Literature summary for 6.3.2.5 extracted from

  • Brown, G.M.
    The metabolism of pantothenic acid (1959), J. Biol. Chem., 234, 370-378.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Bacteria
-
-
-
Escherichia coli
-
-
-
Mammalia
-
-
-
Morganella morganii
-
-
-
no activity in Lactobacillus arabinosus
-
-
-
no activity in Lactobacillus helveticus
-
-
-
no activity in Saccharomyces cerevisiae
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Rattus norvegicus
-
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (R)-4'-phosphopantothenate + 2-aminoethanethiol disulfide
-
Rattus norvegicus ?
-
?
ATP + (R)-4'-phosphopantothenate + 2-aminoethanethiol disulfide 10% of activity compared to L-Cys Morganella morganii ?
-
?
ATP + (R)-4'-phosphopantothenate + 2-methylcysteine
-
Rattus norvegicus N-(phosphopantothenyl)-alpha-methylcysteine + ADP + phosphate
-
?
ATP + (R)-4'-phosphopantothenate + 2-methylcysteine 10% of the activity compared to L-cysteine Morganella morganii N-(phosphopantothenyl)-alpha-methylcysteine + ADP + phosphate
-
?
ATP + (R)-4'-phosphopantothenate + beta-mercaptoethylamine
-
Rattus norvegicus phosphopantetheine + ADP + phosphate
-
?
ATP + (R)-4'-phosphopantothenate + beta-mercaptoethylamine 25% of activity compared to L-Cys Morganella morganii phosphopantetheine + ADP + phosphate
-
?
ATP + (R)-4'-phosphopantothenate + cystine 5% of activity compared to L-Cys Morganella morganii (R)-4'-phosphopantothenoyl-L-cystine + ADP + phosphate
-
?
ATP + (R)-4'-phosphopantothenate + L-Cys
-
Rattus norvegicus (R)-4'-phosphopantothenoyl-L-cysteine + ADP + phosphate
-
?
ATP + (R)-4'-phosphopantothenate + L-Cys mammalian enzyme differs from the bacterial enzyme in that it can use any of the other nucleotide triphosphates equally as well as CTP Mammalia (R)-4'-phosphopantothenoyl-L-cysteine + ADP + phosphate
-
?
CTP + (R)-4'-phosphopantothenate + L-Cys CTP specifically required Mammalia (R)-4'-phosphopantothenoyl-L-cysteine + CDP + phosphate
-
?
CTP + (R)-4'-phosphopantothenate + L-Cys CTP specifically required Escherichia coli (R)-4'-phosphopantothenoyl-L-cysteine + CDP + phosphate
-
?
CTP + (R)-4'-phosphopantothenate + L-Cys CTP specifically required Morganella morganii (R)-4'-phosphopantothenoyl-L-cysteine + CDP + phosphate
-
?
CTP + (R)-4'-phosphopantothenate + L-Cys mammalian enzyme differs from the bacterial enzyme in that it can use any of the other nucleotide triphosphates equally as well as CTP Bacteria (R)-4'-phosphopantothenoyl-L-cysteine + CDP + phosphate
-
?