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Literature summary for 6.3.2.40 extracted from

  • Lerbs, W.; Luckner, M.
    Cyclopeptine synthetase activity in surface cultures of Penicillium cyclopium (1985), J. Basic Microbiol., 25, 387-91 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 ATP + S-adenosyl-L-methionine + anthranilate + L-phenylalanine Penicillium cyclopium
-
cyclopeptine + 2 AMP + 2 diphosphate + S-adenosyl-L-homocysteine
-
?
2 ATP + S-adenosyl-L-methionine + anthranilate + L-phenylalanine Penicillium cyclopium SM 72
-
cyclopeptine + 2 AMP + 2 diphosphate + S-adenosyl-L-homocysteine
-
?

Organism

Organism UniProt Comment Textmining
Penicillium cyclopium
-
-
-
Penicillium cyclopium SM 72
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hypha
-
Penicillium cyclopium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ATP + S-adenosyl-L-methionine + anthranilate + L-phenylalanine
-
Penicillium cyclopium cyclopeptine + 2 AMP + 2 diphosphate + S-adenosyl-L-homocysteine
-
?
2 ATP + S-adenosyl-L-methionine + anthranilate + L-phenylalanine
-
Penicillium cyclopium SM 72 cyclopeptine + 2 AMP + 2 diphosphate + S-adenosyl-L-homocysteine
-
?

Synonyms

Synonyms Comment Organism
cyclopeptine synthetase
-
Penicillium cyclopium

General Information

General Information Comment Organism
metabolism key enzyme of benzodiazepine alkaloid biosynthesis in Penicillium cyclopium Penicillium cyclopium