Crystallization (Comment) | Organism |
---|---|
structure of unliganded enzyme to 2.3 A resolution, of Ddl with adenylyl imidodiphosphate to 2.6 A resolution, of Ddl with ADP to 2.2 A resolution, of Ddl with ADP and D-Ala to 1.9 A resolution, and of Ddl with ATP and D-Ala-D-Ala to 2.3 A resolution. The central domain rotates as a rigid body towards the active site in a cumulative manner in concert with the local conformational change of three flexible loops depending upon substrate or product binding, resulting in an overall structural change from the open to the closed form through semi-open and semi-closed forms | Thermus thermophilus HB8 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus thermophilus HB8 | Q5SHZ3 | - |
- |