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Literature summary for 6.3.2.4 extracted from

  • Perichon, B.; Casadewall, B.; Reynolds, P.; Courvalin, P.
    Glycopeptide-resistant Enterococcus faecium BM4416 is a VanD-type strain with an impaired D-alanine:D-alanine ligase (2000), Antimicrob. Agents Chemother., 44, 1346-1348.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 6.3.2.4

Protein Variants

Protein Variants Comment Organism
additional information insertion in the middle of the ddl gene is responsible for inactivation of D-alanine-D-alanine ligase in strain BM4416 Enterococcus faecium

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + D-alanine Enterococcus faecium
-
 ADP + phosphate + D-alanyl-D-alanine
-
 ?
ATP + D-alanine Enterococcus faecium BM4416
-
 ADP + phosphate + D-alanyl-D-alanine
-
 ?

Organism

Organism UniProt Comment Textmining
Enterococcus faecium
-
-
-
Enterococcus faecium BM4416
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-alanine
-
 Enterococcus faecium ADP + phosphate + D-alanyl-D-alanine
-
 ?
ATP + D-alanine
-
 Enterococcus faecium BM4416 ADP + phosphate + D-alanyl-D-alanine
-
 ?