Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Al3+ | 40% residual activity | Plasmodium berghei | |
Ba2+ | 27% residual activity | Plasmodium berghei | |
Cd2+ | complete inhibition | Plasmodium berghei | |
Chloroquine | 0.1 mM, 24% inhibition | Plasmodium berghei | |
Co2+ | complete inhibition | Plasmodium berghei | |
Cu2+ | 15% residual activity | Plasmodium berghei | |
Fe3+ | 24% residual activity | Plasmodium berghei | |
glutathione | noncompetitive | Plasmodium berghei | |
Hg2+ | complete inhibition | Plasmodium berghei | |
mefloquine | 0.1 mM, 21% inhibition | Plasmodium berghei | |
additional information | no significant inhibition: amoxycillin, gentamycin, streptomycin, kanamycin, tetracycline, penicillin, artesunate, aablaquine and primaquine | Plasmodium berghei | |
Ni2+ | complete inhibition | Plasmodium berghei |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.33 | - |
ATP | pH 8.2, temperature not specified in the publication | Plasmodium berghei | |
0.43 | - |
Gly | pH 8.2, 37°C | Plasmodium berghei | |
8.3 | - |
gamma-L-Glu-L-Cys | pH 8.2, 37°C | Plasmodium berghei |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
70000 | - |
gel filtration | Plasmodium berghei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium berghei | - |
- |
- |
Purification (Comment) | Organism |
---|---|
from Plasmodium berghei infected mouse erythrocytes | Plasmodium berghei |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
29.95 | - |
pH 8.2, 37°C | Plasmodium berghei |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + gamma-L-Glu-L-Cys + Gly | - |
Plasmodium berghei | ADP + phosphate + glutathione | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | x * 70000, SDS-PAGE | Plasmodium berghei |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Plasmodium berghei |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
10 min, no residual activity | Plasmodium berghei |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | 8.5 | - |
Plasmodium berghei |