Literature summary for 6.3.2.23 extracted from

  • Frendo, P.; Jimenez, M.J.; Mathieu, C.; Duret, L.; Gallesi, D.; Van de Sype, G.; Herouart, D.; Puppo, A.
    A Medicago truncatula homoglutathione synthetase is derived from glutathione synthetase by gene duplication (2001), Plant Physiol., 126, 1706-1715.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Medicago truncatula

Engineering

Protein Variants Comment Organism
L534A increased production of glutathione and reduced formation of homglutathione Medicago truncatula
L534A/P535A as compared with L534A mutant, even further increased production of glutathione and further reduced formation of homglutathione Medicago truncatula

Organism

Organism UniProt Comment Textmining
Medicago truncatula Q9XEB8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + gamma-L-glutamyl-L-cysteine + beta-alanine
-
Medicago truncatula ADP + phosphate + gamma-L-glutamyl-L-cysteinyl-beta-alanine
-
?
ATP + gamma-glutamylcysteine + glycine
-
Medicago truncatula ADP + phosphate + gamma-glutamylcysteinylglycine
-
?