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Literature summary for 6.3.2.2 extracted from
- Ethanol-induced expression of glutamate-cysteine ligase catalytic subunit gene is mediated by NF-kappaB (2009), Toxicol. Lett., 185, 110-115.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | presence of an ethanol-responsive element in the human GCL catalytic subunit promoter, it spannes bases 1432 to 832 in hepatocytes and HepG2 cells transfected with cytochrome P450 2E1. The region lacks an ARE but has a putative nuclear factor-kappaB element | up |
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Release 2023.1 (January 2023)
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